|Disease Areas:||Motor Neurone Disease|
|Thematic Area:||Diagnostics, Therapeutics|
|Areas of expertise:||non-coding RNA, tiRNA, Molecular biology, Cell biology|
Elisabeth is a PhD student under the supervision of Professor Jochen Prehn. She holds a Master of Science in Biotechnology Engineering from Lund University in Sweden. Her research focuses on the role of tiRNAs in motor neurone disease (MND). tiRNAs are a newly discovered class of small non-coding RNAs which are generated in response to cellular stress and impaired tiRNA production is linked to neurodegeneration. The aim of her PhD is to investigate the disease-specific ‘fingerprint’ of tiRNAs in disease models of MND and to explore their function in neuronal stress responses, with the long-term goal to deliver novel prognostic and diagnostic biomarkers and therapeutic targets for MND. Her PhD is funded by the RCSI StAR International PhD programme.