Jennifer Dowling
Epilepsy, Multiple Sclerosis, RCSI, Research Fellows
Disease Areas:Epilepsy, Multiple Sclerosis, Cerebal Palsy
Thematic Area:Therapeutics
Areas of expertise:Inflammasomes, Innate Immunity, Neuroimmunology, inflammation

Jennifer is a Marie Skłodowska-Curie Actions Individual Fellow in FutureNeuro and Honorary Lecturer in the School of Pharmacy and Biomolecular Sciences in RCSI. Jennifer obtained her BSc in Biotechnology from DCU and was awarded an IRC scholarship to complete her PhD in Immunology at the University. After completing her PhD in 2009, Jennifer joined Professor Luke O’Neill’s Inflammation Research Group in TCD where she began examining the regulation of a potent inflammatory complex known as the, ‘the Inflammasome’ in macrophage cells, a cell type of the immune system. Jennifer then went to the Hudson Institute of Medical Research, Melbourne, Australia in 2013 to further her work on inflammasomes and inflammatory responses in several disease states including hypertension, bacterial and viral infection. Jennifer returned to Ireland in 2018 joining Dr Claire McCoy’s Group at RCSI working to elucidate pathways regulating the inflammatory status of macrophage cells in diseases models including multiple sclerosis. Jennifer’s current research is focused on understanding innate neuro-immune interactions and signalling events in the CNS and their influence on neurological outcomes of injury and disease. Most recently, in February 2020, she was awarded a prestigious Marie Sklodowska-Curie Individual Fellowship for her project, ‘OxyBaby’, investigating novel treatments for hypoxic brain injuries that can lead to seizures and the development of Cerebral Palsy in newborns. Jennifer is a committee member of Neuroscience Ireland.

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