Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications


Stefan Wolking Ciarán Campbell Caragh Stapleton Mark McCormack Norman Delanty Chantal Depondt Michael R Johnson Bobby P C KoelemanRoland Krause Wolfram S Kunz Anthony G Marson Josemir W Sander Graeme J Sills Pasquale Striano Federico Zara Sanjay M Sisodiya Gianpiero L Cavalleri Holger Lerche 

Resistance to anti-seizure medications (ASMs) presents a significant hurdle in the treatment of people with epilepsy. Genetic markers for resistance to individual ASMs could support clinicians to make better-informed choices for their patients. In this study, we aimed to elucidate whether the response to individual ASMs was associated with common genetic variation.

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