Zonisamide safety in pregnancy: Data from the UK and Ireland epilepsy and pregnancy register

G McCluskey , M O Kinney, A Russell , W H Smithson , L Parsons , P J Morrison , R Bromley , L MacKillop , C Heath , B Liggan , S Murphy , N Delanty , B Irwin, E Campbell , J Morrow , S J Hunt , J J Craig 

Animal data suggest teratogenic effects with zonisamide use and risk of pregnancy losses. Human data following zonisamide exposure are presently limited, but suggest low risk of malformation with elevated risk of low birth weight.

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