David Henshall

Cristina is currently a Research Fellow and Honorary Lecturer within the Department of Physiology & Medical Physics at Royal College of Surgeons in Ireland (RCSI), and her research interests are on molecular mechanisms of epilepsy and brain targeted drug delivery.

Her education and training was as a Pharmacist and Biochemist (BSc, PharmD), with a M.Sc. and Ph.D. in Pharmacology. Shortly after her Ph.D. (2013), she joined Prof. David Henshall’s group to follow the team’s discoveries on the role of microRNAs in experimental and human epilepsy. Her work has, to date, resulted in discovering the main mechanism by which a specific miR-based therapy produces anti-seizure effects, development of novel oligonucleotide delivery routes for disease-modification, and introduction of new models and research methodologies including in vivo gene expression and imaging technologies.  Currently, Cristina has been successfully leading collaborative projects with a FN industry partner to explore pre-clinical development of a miR-based therapy for epilepsy.

Cristina is junior member of the International League Against Epilepsy (ILAE) / American Epilepsy Society (AES) Translational Task Force (systematic review), and is leading the Basic Sciences Workpackage of the ILAE/Young Epilepsy Section (YES) Translational Database and Scientific Exchanges Task Force. Her work has also been extensively internationally recognized and she received a number of awards, specifically the Grass Young Investigator Award 2017 (endowed by AES), and Harinarayan Young Neuroscientist Award 2015 (endowed by ILAE).

Research Areas