Here at FutureNeuro, we bring together the brightest research talent in neuroscience, clinical neurology, genetics, cell biology, materials chemistry and patient data analytics. Our scientists and clinicians engage with patients, healthcare providers, industry partners and policy makers to reduce the individual,societal and economic burden of neurological diseases.
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We are funded by Science Foundation Ireland and based at the Royal College of Surgeons in Ireland, with teams located in Trinity College Dublin, UCD, DCU and NUI Galway.
Post-Doctoral Researcher Investigating the role of RNA modifications in epilepsy
Tenure: 18 months
Salary: €37,874 – €40,221 per annum
Location: UCD School of Biomolecular and Biomedical Science
Reporting to: Dr. Gary Brennan
Start Date: TBC
Epilepsy-inciting events such as status epilepticus, traumatic brain injury and stroke are known to disrupt patterns of neuronal and non-neuronal gene expression and gene expression regulation. Recent research by the team has focussed on epigenetic and microRNA-mediated control of gene expression in epilepsy as well as biomarker development.
The current project will specifically explore the role of post-transcriptional modifications of RNA and how they contribute to the development of epilepsy. Using a combination of in vivo and in vitro approaches the successful applicant will explore how RNA modifications regulate neuronal function and structure via regulation of protein translational efficiency and the role of post-transcriptional gene regulation in epilepsy development.
Candidates with experience with epilepsy models (both in vivo and in vitro) are especially encouraged to apply. Candidates will also use a combination of confocal microscopy, next-generation sequencing, mass spectrometry and standard molecular and biochemical techniques.
This is a research focused role, where you will conduct a specified programme of research supported by research training and development under the supervision and direction of a Principal Investigator.
The primary purpose of the role is to further develop your research skills and competences, including the processes of publication in peer-reviewed academic publications, the development of funding proposals, the mentorship of graduate students along with the opportunity to develop your skills in research led teaching.
Apply on the UCD website. Job reference 012547