Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression.

Quantification of substoichiometric modification reveals global tsRNA hypomodification, preferences for angiogenin-mediated tRNA cleavage, and idiosyncratic epitranscriptomes of human neuronal cell-lines.

A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies.

Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data.

Shaping the future of European epilepsy research: Final meeting report from EPICLUSTER.

Lithium carbonate in amyotrophic lateral sclerosis patients homozygous for the C-allele at SNP rs12608932 in UNC13A: protocol for a confirmatory, randomized, group-sequential, event-driven, double-blind, placebo-controlled trial.

Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.

Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications.

The role of common genetic variation in presumed monogenic epilepsies.

Patient perspectives on digital healthcare technology in care and clinical trials for motor neuron disease: an international survey.

Evaluation of policies and practices to support safe and appropriate analgesic and sedative prescribing: The CDRx (controlled drug prescribing) protocol.

The population genomic legacy of the second plague pandemic.

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3-WG4 omics working group of the ILAE/AES joint translational TASK force.

A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3-WG4 omics working group of the ILAE/AES joint translational TASK force.

Transdiagnostic inflammatory subgroups among psychiatric disorders and their relevance to role functioning: a nested case-control study of the ALSPAC cohort.

Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice.

Life-span characterization of epilepsy and comorbidities in Dravet syndrome mice carrying a targeted deletion of exon 1 of the Scn1a gene.

Rare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy.

Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype.

AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome.

Modelling α-Synuclein Aggregation and Neurodegeneration with Fibril Seeds in Primary Cultures of Mouse Dopaminergic Neurons.

Association between social deprivation and incidence of first seizures and epilepsy: A prospective population-based cohort.

Investigation of MicroRNA-134 as a Target against Seizures and SUDEP in a Mouse Model of Dravet Syndrome.

Expert Perspective: Who May Benefit Most From the New Ultra Long-Term Subcutaneous EEG Monitoring?

Molecular Signatures of Response to Mecasermin in Children With Rett Syndrome.

A retrospective study of the correlation between duration of monitoring in the epilepsy monitoring unit and diagnostic yield.

Sturge-Weber syndrome: Case report, literature review and proposed pregnancy care plan.

Electrochemiluminescent detection of epilepsy biomarker miR-134 using a metal complex light switch.

Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank.

BICS01 Mediates Reversible Anti-seizure Effects in Brain Slice Models of Epilepsy.

BOK controls ER proteostasis and physiological ER stress responses in neurons.

A Clinical Decision Support System for the Prediction of Quality of Life in ALS.

Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction.

Fifteen-minute consultation: Diagnosing serious pathology in children with headaches presenting to the emergency department.

Whole exome sequencing studies in epilepsy: A deep analysis of the published literature.

Parenting a newborn baby during the COVID-19 pandemic: a qualitative survey.

MicroRNA inhibition using antimiRs in acute human brain tissue sections.

Beyond Seizure Control: Treating Comorbidities in Epilepsy via Targeting of the P2X7 Receptor.

Glutamate NMDA Receptor Antagonists with Relevance to Schizophrenia: A Review of Zebrafish Behavioral Studies.

Tuberous Sclerosis: A Rare Disease with an Orphan Complex.

Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain.

Hypoglycaemic events resembling focal seizures -A case report and literature review.

Germline mosaicism in a family with MBD5 haploinsufficiency.

Epigenetic genes and epilepsy – emerging mechanisms and clinical applications.

Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With KCNC2 Pathogenic Variants.

KBG syndrome mimicking genetic generalized epilepsy.

Topographic divergence of atypical cortical asymmetry and atrophy patterns in temporal lobe epilepsy.

Genomic analysis of “microphenotypes” in epilepsy.

Immunohistochemical Analysis of Tight Junction Proteins.

Genomics in the presurgical epilepsy evaluation.

Acetazolamide: Old drug, new evidence?

Purinergic Signalling and Inflammation-Related Diseases.

A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam.

Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Expert Perspective: Who May Benefit Most From the New Ultra Long-Term Subcutaneous EEG Monitoring?

Whole exome sequencing studies in epilepsy: A deep analysis of the published literature

BICS01 Mediates Reversible Anti-seizure Effects in Brain Slice Models of Epilepsy

Inherent P2X7 Receptors Regulate Macrophage Functions during Inflammatory Diseases

Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice

Biomaterial and Therapeutic Approaches for the Manipulation of Macrophage Phenotype in Peripheral and Central Nerve Repair

Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions

Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual

International Recommendations for the Management of Adults Treated With Ketogenic Diet Therapies

Hypoglycaemic events resembling focal seizures -A case report and literature review

Epilepsy in the mTORopathies: opportunities for precision medicine

Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy

Genomic Analysis of “Microphenotypes” in Epilepsy

Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides

A Road Map for Remote Digital Health Technology for Motor Neuron Disease

NRXN1α +/- is associated with increased excitability in ASD iPSC-derived neurons

Concordance between PCR-based extraction-free saliva and nasopharyngeal swabs for SARS-CoV-2 testing

Causes and classification of first unprovoked seizures and newly-diagnosed epilepsy in a defined geographical area- an all-comers analysis

tRNA-derived fragments: A new class of non-coding RNA with key roles in nervous system function and dysfunction

tsRNAsearch: A pipeline for the identification of tRNA and ncRNA fragments from small RNA-sequencing data

Impact of the COVID-19 pandemic on people with epilepsy: Findings from the Brazilian arm of the COV-E study

Exploring the prevalence and profile of epilepsy across Europe using a standard retrospective chart review: Challenges and opportunities

IgG 1 pan-neurofascin antibodies identify a severe yet treatable neuropathy with a high mortality

A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies

Progressive Mitochondrial SOD1 G93A Accumulation Causes Severe Structural, Metabolic and Functional Aberrations through OPA1 Down-Regulation in a Mouse Model of Amyotrophic Lateral Sclerosis

Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study

Neuroprotective Effect of Taurine against Cell Death, Glial Changes, and Neuronal Loss in the Cerebellum of Rats Exposed to Chronic-Recurrent Neuroinflammation Induced by LPS

Challenging the Established Order: Innovating Clinical Trials for Amyotrophic Lateral Sclerosis

Democratizing epilepsy care: Utility and usability of an electronic patient portal

Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy

Post-ictal psychosis in epilepsy: A clinico-genetic study

Predictive modelling of hypoxic ischaemic encephalopathy risk following perinatal asphyxia

Democratizing epilepsy care: Utility and usability of an electronic patient portal

Zonisamide safety in pregnancy: Data from the UK and Ireland epilepsy and pregnancy register

Stick or twist: Everolimus for seizures in tuberous sclerosis complex during the COVID-19 pandemic

tRNA-derived fragments: A new class of non-coding RNA with key roles in nervous system function and dysfunction

Biosensors Designed for Clinical Applications

Genome-Wide Association Study Identifies Risk Loci for Cluster Headache

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

ATP and adenosine—Two players in the control of seizures and epilepsy development

Regulatory Mechanisms of the RNA Modification m 6 A and Significance in Brain Function in Health and Disease

Computed tomography and emergency department frequency in homeless patients with seizures

Prediction of caregiver quality of life in amyotrophic lateral sclerosis using explainable machine learning

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

Precision therapy in the genetic epilepsies of childhood

Wireless electrochemiluminescence at functionalised gold microparticles using 3D titanium electrode arrays

Opportunities and challenges for microRNA-targeting therapeutics for epilepsy

Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillation

Assessing the role of rare genetic variants in drug-resistant, non-lesional focal epilepsy

Reversible male infertility with valproate use: A review of the literature

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

AMPK-regulated miRNA-210-3p is activated during ischaemic neuronal injury and modulates PI3K-p70S6K signalling

Ferrocene-Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics

Limitations of animal epilepsy research models: Can epileptic human tissue provide translational benefit?

Discrete choice experiment for eliciting preference for health services for patients with ALS and their informal caregivers

Climate change and epilepsy: Insights from clinical and basic science studies

Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy

Elevated blood purine levels as a biomarker of seizures and epilepsy

Identification of clinically relevant biomarkers of epileptogenesis — a strategic roadmap

Evaluating risk to people with epilepsy during the COVID-19 pandemic: Preliminary findings from the COV-E study

Ictal asystole during long-term video-EEG; semiology, localization, and intervention

The anatomy of electronic patient record ethics: a framework to guide design, development, implementation, and use

Will RNA circles run rings around microRNA?

Engineering Calcium Signaling of Astrocytes for Neural-Molecular Computing Logic Gates

Security in Brain-Computer Interfaces: State-of-the-Art, Opportunities, and Future Challenges

Coproducing health and well-being in partnership with patients, families, and healthcare providers: A qualitative study exploring the role of an epilepsy patient portal

Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse

Electrochemical Properties of Screen-Printed Carbon Nano-Onion Electrodes

Examination and diagnosis of electronic patient records and their associated ethics: a scoping literature review

Analysis of the aetiology of epilepsy in 3,216 adult patients attending a tertiary referral center enabled by an electronic patient record

Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy

P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice

White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study

Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury

TRICALS: creating a highway toward a cure

Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy

Location-specific reflex epilepsy: a novel reflex epilepsy phenotype

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

Incidence of first seizures, epilepsy, and seizure mimics in a geographically defined area

MicroRNAs as regulators of brain function and targets for treatment of epilepsy

Generation of three induced pluripotent stem cell (iPSC) lines from a patient with developmental epileptic encephalopathy due to the pathogenic KCNA2 variant c.869T>G; p.Leu290Arg (NUIGi052-A, NUIGi052-B, NUIGi052-C)

Prevalence of N-Methyl-d-Aspartate Receptor antibody (NMDAR-Ab) encephalitis in patients with first episode psychosis and treatment resistant schizophrenia on clozapine, a population based study

The ENIGMA‐Epilepsy working group: Mapping disease from large data sets

RCPCH Stroke in Childhood Guidelines: how well are these being followed?

Quantification of tRNA fragments by electrochemical direct detection in small volume biofluid samples

Effectiveness and tolerability of adjunctive brivaracetam in patients with focal seizures: Second interim analysis of 6-month data from a prospective observational study in Europe

Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study

Epigenetics explained: a topic “primer” for the epilepsy community by the ILAE Genetics/Epigenetics Task Force

A comparison of genomic diagnostics in adults and children with epilepsy and comorbid intellectual disability

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

Generation of twelve induced pluripotent stem cell lines from two healthy controls and two patients with sporadic amyotrophic lateral sclerosis

SJS/TEN 2019: From science to translation

Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration

Testing association of rare genetic variants with resistance to three common antiseizure medications

Could the 2017 ILAE and the four-dimensional epilepsy classifications be merged to a new “Integrated Epilepsy Classification”?

Prediction of caregiver burden in amyotrophic lateral sclerosis: a machine learning approach using random forests applied to a cohort study

Derivation of two iPSC lines from a sporadic ASD patient (NUIGi033-A) and a paternal control (NUIGi034-A)

Plasma microRNA levels in male and female children with cystic fibrosis

Differential Expression of the Metabotropic P2Y Receptor Family in the Cortex Following Status Epilepticus and Neuroprotection via P2Y 1 Antagonism in Mice

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus

The Role of Microglia in Neurodevelopmental Disorders and their Therapeutics

Epilepsy Benchmarks Area III: Improved Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects

ATP Measurement in Cerebrospinal Fluid Using a Microplate Reader

Igniting intersectoral collaboration in chronic disease management: a participatory action research study on epilepsy care in Ireland

Derivation of familial iPSC lines from three patients with retinitis pigmentosa carrying an autosomal dominant RPE65 mutation (NUIGi027-A, NUIGi028-A, NUIGi029-A)

Epigenetics and noncoding RNA: Recent developments and future therapeutic opportunities

Imaging tripartite synapses using super-resolution microscopy

De-novo mutations in patients with chronic ultra-refractory epilepsy with onset after age five years

Exploring the genetic overlap between psychiatric illness and epilepsy: A review

Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A

Are patients ready for integrated person-centered care? A qualitative study of people with epilepsy in Ireland

Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment

Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer’s disease

The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia

GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model

Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model

Targeting microRNA-134 for seizure control and disease modification in epilepsy

Development of a genomics module within an epilepsy‐specific electronic health record: Toward genomic medicine in epilepsy care

Electrical stimulation of the ventral hippocampal commissure delays experimental epilepsy and is associated with altered microRNA expression

Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy

MicroRNAs as biomarkers and treatment targets in status epilepticus

Elevation of plasma tRNA fragments precedes seizures in human epilepsy

Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y1 Receptor in Experimental Epilepsy

Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures

A genome‐wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine

De-novo mutations in patients with chronic ultra-refractory epilepsy with onset after age five years

Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

Regulation of P2X7 receptor expression and function in the brain

Normal cerebral cortical thickness in first-degree relatives of temporal lobe epilepsy patients

Discovery and validation of blood microRNAs as molecular biomarkers of epilepsy: Ways to close current knowledge gaps

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus

Eslicarbazepine acetate as monotherapy in clinical practice: Outcomes from Euro‐Esli

Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA‐134

The phenotype of bilateral hippocampal sclerosis and its management in “real life” clinical settings

Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer

Haploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels

Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform

Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study

The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland

Psychiatric and psychosocial morbidity 1 year after epilepsy surgery

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