Our Research

Here at FutureNeuro, our research is focused on providing faster diagnostics, personalised therapeutics and patient-centred care for people with chronic and rare neurological diseases, under our three themes of Diagnostics, Therapeutics and eHealth. 

We bring together internationally recognised neuroscientists, geneticists, cell-biologists, analytical and materials chemists from five third level institutions, as well as a wide network of clinicians across Ireland. We work in the areas of Epilepsy, Motor Neurone Disease and Parkinsons, but our researchers also have expertise in Multiple Sclerosis, Alzheimer’s and psychosis. 

Research Themes

Our aim in FutureNeuro is to provide faster diagnostics, precision therapeutics and eHealth enabled solutions for those with chronic and rare neurological diseases. These themes are at the core of all of our research activities.

Diagnostics

Under our Diagnostics theme, our research is:

  • identifying the genetic causes of neurological diseases
  • discovering blood-based biomarkers of neurological diseases
  • developing technology for rapid point-of-care diagnostics

Through our unique clinical network, we are translating genetic diagnostics to the Irish health system. We are sequencing patients’ genomes to identify precise genetic causes and working with industry partners to improve the diagnostic yield of genetic testing.

Our researchers have discovered how molecules released from the brain enter the bloodstream act as early warning systems for seizures. They are now working with our material chemists to develop seizure detection technology that could be used in home and clinical settings.

Therapeutics

Under our Therapeutics theme, our research is:

  • providing a new network-based perspective on neuro-degeneration
  • designing new therapeutics that restore normal brain excitability
  • advancing neuronal stem cell technology to discover drug treatments for rare neurological disease

Our researchers are identifying neurophysiology-based biomarkers for Motor Neurone disease. We are using non-invasive neuro-electric signals to examine the disruption of brain networks and studying small brain molecules, such as MicroRNAs which regulate the activity of complex gene networks in brain cells. We are using induced pluripotent stem cell technologies to grow neurons from a skin biopsy and working with industry partners to screen existing and emerging treatments for rare diseases.

eHealth

Under our eHealth theme, our research is:

  • driving proactive, precision and personalised medicine

  • building an Electronic Patient Record (EPR) for Motor Neurone disease

We are putting the patient at the centre of the clinical and research network. We are leveraging mainstream technology to support better self-care for people with neurological diseases and collecting clinical data, which is enabling diagnostic and therapeutic research.

Using patient registers, we are facilitating collaborative research with trial-ready patients and facilitating more comprehensive data collection and integration of care.