About FutureNeuro

Our Vision

Enable people with Neurological Diseases to live independently

Our Mission

Faster Diagnosis, Personalised Treatments and Patient-Centred Care

About Us

 We aim to change the patient journey through research informed by the needs of both patients and neurologists. This includes developing rapid and accurate tools for diagnosis, the development of therapies to correct damaged brain networks, technologies to enable patients to monitor their own health and well-being, and linking this to Ireland’s national imaging, diagnostics and eHealth infrastructure.

We are multi-disciplinary, inter-institutional and working with industry, patient organisations and the health service to transform the lives of patients in Ireland and worldwide.

We focus on epilepsy, a chronic brain disease-affecting people of all ages, and ALS (also known as motor neurone disease), a rare neurodegenerative disease, which can be viewed as a model of more common neurodegenerations in terms of shared pathomechanisms, clinical pathways and patient journey. This unique approach has proven a powerful strategy for discovery that, along with our underpinning technology platforms and national clinical network, allows us to scale to other neurological disorders. That process has begun, with research underway on Parkinson’s disease, Multiple Sclerosis and other rare neurological diseases.

Our Themes

FutureNeuro conducts research in three thematic areas:

Diagnostics: Provision of an accurate molecular diagnosis through the discovery of genetic and circulating biomarkers of disease and developing technology for their detection.

Therapeutics: Discovery of novel and disease-modifying treatments that target hyperexcitable and damaged brain networks, optimizing treatment and clinical trials.

eHealth: Delivery of proactive, personalised and precision patient management and the development of research-enabled healthcare systems and connected health solutions to improve care, enrich research and facilitate clinical trials.

Diagnostics

Our Diagnostics research looks at applying sequencing and advanced informatics and nanomaterials technology to discover, detect and interpret biomolecules from patients collected via national clinical networks to deliver faster, more accurate diagnosis.

Therapeutics

Our Therapeutics research is exploring new types of therapies,  including molecules that work by controlling the activity of networks of genes to stabilize or recover brain function to see how we could deliver these to the brain. 

eHealth

Our eHealth research aims to deliver a research-adapted continuously learning and innovative healthcare system through careful design, development and implementation of eHealth technologies.

Our People

We bring together the brightest research talent in neuroscience, clinical neurology, genetics, cell biology, materials chemistry and patient data analytics, led by our team of cross-intitutional principal investigators.

David Henshall

David Henshall

Gianpiero Cavalleri

Gianpiero Cavalleri

Jochen Prehn

Jochen Prehn

Orla Hardiman

Orla Hardiman

Matthew Campbell

Matthew Campbell

Colin Doherty

Colin Doherty

Robert Forster

Robert Forster

Sanbing Shen

Sanbing Shen

Clinical Network

FutureNeuro clinical neurologists, spanning the main adult and paediatric hospitals across Ireland, represent the advanced clinical care of patients with neurological diseases. Located in the national tertiary neurology treatment centres and key regional hospitals, they bring expertise in clinical neurology, epilepsy, ALS, Alzheimer’s disease, MS, psychosis. Through our clinical network, our platform and industry research is enabled with:

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Patient registers providing well-defined and stratified patient cohorts

  • National Epilepsy Electronic Patient Record (EPR) developed since 2009. Rich source of longitudinal epilepsy care data > 10,000 patients (Phenotype, AED history, comorbidities, seizure history).
  • Irish ALS register >1,400 patients enrolled since 1993
  • MS register (emerging)
  • Rare neurological disease register (emerging)
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Deep patient phenotyping and genotyping correlations

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Clinical trials expertise

  • Patient recruitment
  • Clinical Research Centre support
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Remote seizure-monitoring and in-patient video monitoring unit

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Integration with International research network

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Biosamples collection (blood, tissue, CSF) for genetic diagnosis, precision therapeutics and gene discovery.

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First seizure clinics

Our Institutes

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Diseases

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International Collaboration

Organisations we work with

Our Governance

Governance Committee
Industry
FutureNeuro Executive Committee